Clenbuterol belongs to the so-called beta-2 agonists. Its chemical structure resembles adrenaline. It stimulates beta-2 receptors in the sympathetic nervous system, causing relaxation of smooth muscle tissue, especially in the bronchi and uterus. Compared to other beta-2 agonists, Clenbuterol has a longer half-life, higher gastrointestinal half-life, and better absorption from the gastrointestinal tract.
Beta-2 agonists are used to treat bronchial asthma and prevent preterm labor. Clenbuterol is taken orally. It is mainly used in veterinary medicine, for example to treat asthma in horses. Clenbuterol is not used to treat asthma in humans. Clenbuterol has also been used illegally to raise livestock and to dilute drugs such as heroin.
There have been attempts to produce clenbuterol drugs for diseases that reduce muscle mass, such as sarcopenia, HIV, and cancer. However, the potential effects of clenbuterol on the heart have been a barrier to treatment.
Some beta-2 agonists, like clenbuterol, are weakly anabolic, meaning they stimulate tissue growth. They increase the protein content of burned muscles by causing glycogen to be “burned” simultaneously in muscle and body fat stores. Therefore, Clenbuterol is one of the most commonly used substances to promote muscle growth.
Muscular system: fine muscular tremor. CNS: anxiety, headache. Cardiovascular system: decrease or increase in blood pressure, tachycardia, angina pain, ventricular extrasystoles. Skin and mucous membranes: rash, swelling of the face, urticaria. Circulatory system: thrombocytopenia, hypoglycemia. Digestive system: gastritis, diarrhea, dry mouth, nausea. Genitourinary system: violation of urination. The described side effects disappear without stopping treatment, 1 to 2 weeks after their onset.
The drug contains so-called parabens as excipients: methyl parahydroxybenzoate and propyl parahydroxybenzoate, which can cause urticaria and contact dermatitis (delayed-type allergic reactions). In rare cases, immediate allergic reactions (bronchospasm) may occur. The drug contains glycerol as an excipient, which in large doses can cause headaches, stomach irritation and diarrhea. The drug contains 0.63% by volume of ethyl alcohol. Each dose contains 0.005 g of alcohol per 1 ml. It is dangerous for people with liver disease, alcoholism, epilepsy, brain damage or disease, as well as pregnant women and children. May increase the effect of other drugs. The drug is not suitable for patients with congenital fructose intolerance due to the presence of sorbitol. Influence on driving ability and control mechanisms During the first days of treatment, clenbuterol may cause slight tremors and anxiety, which requires greater caution when driving a car and driving. use of machinery.